In Spell it!, one player rolls the five alphabet dice each round, then everyone tries to think of a word that uses three of the five letters in a word that fits the theme. The themes include: "Home Sweet Home", "Around the World", "Famous People", "Sports, Games, and Hobbies", "Create a Theme" and "No Nouns".

If you call out a word that matches the theme, you win a chip equal to the total number of letters used in that word.